The skull is a prop in Vasquez Castle.
The skull is a realistic prop of a human skull. It is a bone color with signs of aging, including discoloration and cracking, that make it appear original to the castle.
Scooby-Doo, Where Are You!
While searching for Daphne Blake, Shaggy Rogers and Scooby-Doo lagged behind Fred Jones and Velma Dinkley, getting lost. After Shaggy wondered where the latter two were, a skull propped up onto some books on top of a dressing table told them, "Thataway". Shaggy politely thanked "him", with it responding, "S'awright". They quickly realised it was a talking skull and ran away -- into another spooky encounter.
- This is the first time a skull prop is used to scare intruders away and then imply that it could be real. It's possible that is operating it, even though he doesn't explicitly reveal that at the end, but presumably that was to keep it a mystery as intended.
- The skull replying, "S'awright", is reference to the tradmark reply Señor Wences's Pedro (the head in a box) does.
- Without hand or eye movement, the skull isn't actually giving any indication of which way to go, so Shaggy's really thanking him for nothing.