The Mutant Bee was the titular insectoid character from one of Vincent Van Ghoul's movies, the Mutant Bee.
The Mutant Bee resembled a bee in humanoid form.
The Mutant Bee was very dangerous.
Powers and abilities
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Scooby-Doo! Mystery Incorporated
Vincent Van Ghoul opened a door and the Mutant Bee came out, along with Dr. Phobos and Professor Jantzen to frighten his house guests. In the middle a huge demon appeared taking them all down, grabbing the Mutant Bee by its arm and cracking it and threw him against the wall. The demon was called Nightfright and told Shaggy, Scooby, and Vincent to die. After Nightfright was unmasked, it was explained he paid Mutant Bee, Dr. Phobos, and Professor Jantzen for being victims.
After Mystery Inc.'s dinner, the Mutant Bee appeared, but it was just Vincent Van Ghoul who arrived with dessert.