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A haunting need for images
Disguise tricks are a standard survival trick for characters with sufficient command of toon physics. When they are being chased by an enemy and can get out of sight for a moment, they can pull disguises from nowhere and improvise a situation. The enemy will be completely taken in, at least for a little while. Scooby-Doo and Shaggy Rogers are well known for using disguises to comedically outwit the ghosts.
Older cartoon characters such as Bugs Bunny are the real masters of this trick.
While the crossover episode Scoobynatural didn't feature any disguise tricks within the episode itself, a deleted scene on the Supernatural season 13 DVD contains one where a disguised Scooby, Shaggy and Dean Winchester serve the ghost dinner until Dean sprinkles salt on the ghost, a ghost weakness and exposes them, forcing the three to run.